By L. Qin, Harry K. Genant, J.F. Griffith, K.S. Leung
This booklet presents a point of view at the present prestige of bioimaging applied sciences constructed to evaluate the standard of musculoskeletal tissue with an emphasis on bone and cartilage. It bargains reviews of scaffold biomaterials built for boosting the fix of musculoskeletal tissues. those bioimaging suggestions comprise micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which offer not just 2-D and three-D photographs of the comparable organs or tissues, but in addition quantifications of the suitable parameters. the improvement bioimaging applied sciences constructed for the above purposes also are prolonged through incorporating imaging contrast-enhancement fabrics. hence, this e-book will offer a distinct platform for multidisciplinary collaborations in schooling and joint R&D between numerous professions, together with biomedical engineering, biomaterials, and easy and scientific medication.
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Extra resources for Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials: Techniques and Applications
Chao Hip Joint Contact Pressure in Activities of Daily Living Intrinsic pathomechanical changes in articular cartilage and subchondral bone depend upon local stress levels rather than global joint loading. To estimate the acetabulam and femoral head contact area and pressure distribution under daily activities is essential in predicting joint disease progression, patient management and pre-treatment planning in patients at diﬀerent stages of osteonecrosis. This loading data provides the biomechanical rationale for femoral head subchondral bone collapse prevention and the selection of an eﬀective method of reconstruction for varying degrees of osteonecrotic involvement.
In addition, bone and joint loading depend on muscle contraction and the interaction among all connective tissues engaged in body and limb functions. This chapter presents a variety of bio-imaging techniques and a number of selected application examples of using these techniques to conduct structure and biomechanical investigations involving the normal and abnormal compositions and functions of the musculoskeletal system. A unique simulation software and database, the Virtual Interactive Musculoskeletal System (VIMS), which incorporates model-making techniques, biomechanical analysis algorithms, and a graphic image-based virtual laboratory environment to present the model, data and analysis results, is introduced.
Bone :– Pothuaud L, Laib A, Levitz P, Benhamou CL, Majumdar S () Three-dimensional-line skeleton graph analysis of high-resolution magnetic resonance images: a validation study from -microm-resolution microcomputed tomography. J Bone Miner Res :– Recker R, Ensrud K, Diem S, Cheng E, Bare S, Masarachia P, Roschger P, Fratzl P, Klaushofer K, Lombardi A, Kimmel D () Normal bone histomorphometry and D microarchitecture after years alendronate treatment of postmenopausal women.
Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials: Techniques and Applications by L. Qin, Harry K. Genant, J.F. Griffith, K.S. Leung